NeuterReady

NeuterReady: Evidence-Based Support for Confident Male Dog Neutering Decisions

NeuterReady, developed by the team at InsituGen, gives veterinary professionals an evidence-based way to assess hormonal maturity in male dogs before neutering.

By measuring androgen activity, not just testosterone, NeuterReady provides a more complete picture of sexual maturity, helping clinicians make informed recommendations that support long-term animal health, behaviour, and welfare.

The key benefits:

Prevents premature neutering and associated risks

Simplifies client communication with clear, data-led results

UK‑exclusive to NationWide Laboratories, ensuring a validated, quality-assured service, trusted access and seamless support

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The Science Behind NeuterReady

NeuterReady: Bringing biology to clinical decision-making

NeuterReady is powered by InsituGen’s proprietary bioassay technology, a biological, not chemical, method that detects androgen receptor activity in plasma or serum samples.

This approach measures total androgenic bioactivity, offering a fuller picture of hormonal maturity than traditional testosterone-only assays.

A Snapshot of Maturity

NeuterReady brings advanced hormone science into everyday practice, offering an accessible, objective way to assess maturity and guide neutering decisions with confidence.

A clearer picture
Uses a biology-based approach, not chemical testing, to measure overall androgen activity, giving a more complete view of hormonal maturity than testosterone alone.

Simple and precise
Just one serum or plasma sample is needed. Submitted via NationWide Laboratories’ standard process, with no special equipment or extra training required. Results are typically available within up to 7 working days.

Aligned with current guidance
Developed to complement updated neutering guidelines, helping veterinary professionals make timing decisions based on measurable hormonal data rather than estimated age.

Supporting long-term wellbeing
Recognises that every dog, and every breed, matures differently. By confirming individual readiness, NeuterReady helps reduce the risks linked with early neutering and supports healthier outcomes over a lifetime.

Supported by Veterinary Experts

NeuterReady is grounded in the latest research and guided by leading voices in veterinary medicine. Clinicians and researchers are calling for a more personalised, evidence-based approach to neutering. NeuterReady supports that shift – offering tools that align with expert insights on the importance of hormonal maturity, individual development, and long-term wellbeing.

How to Use NeuterReady

Real-World Results

Every dog develops differently, and NeuterReady puts that individuality at the centre of neutering decisions.

Clinics using NeuterReady are seeing firsthand how hormonal maturity varies across breeds, ages, and individuals – with real diagnostic results that challenge assumptions and simplify surgical timing.

NeuterReady: Downloadable Resources

Practical tools for clinics and clients

NeuterReady provides supporting materials to help your practice integrate hormonal maturity testing with ease from technical guidance to client-friendly information sheets. Each resource is free to download, print, and share with your veterinary team or pet owners.

Download Resources:

NeuterReady Technical Information Sheet (PDF) – Overview of NeuterReady’s bioassay science, validation, and clinical background.

NeuterReady Technical Information Poster (PDF) – A great resource for your Vets & Staff, perfect for hanging up on your noticeboard.

NeuterReady Pet Owner Information Sheet (PDF) – Easy-to-read summary to help owners understand why hormonal maturity matters.

NeuterReady Pet Owner Information Poster (PDF) – A great resource for Pet-Owners, perfect for hanging up on your reception area.

NeuterReady: Supporting Research

Backed by Veterinary Science and Clinical Evidence

NeuterReady’s approach is supported by published, peer-reviewed research exploring how neutering age impacts health outcomes across breeds and body weights.

These studies form the foundation for a more evidence-based approach to timing neutering decisions in clinical practice.

Key References:

Assisting decision – making on age of neutering for German Short/Wirehaired Pointer, Mastiff, Newfoundland, Rhodesian Ridgeback, Siberian Husky: associated joint disorders, cancers, and urinary incontinence

Assisting decision – Making on Age of Neutering for Mixed Breed Dogs of Five Weight Categories: Associated Joint Disorders and Cancers

Assisting decision – Making on Age of Neutering for 35 Breeds of Dogs: Associated Joint Disorders, Cancers, and Urinary Incontinence

Frequently Asked Questions

The test analyses circulating androgen levels to determine sexual maturity – key indicators for optimal desexing timing.

No, NeuterReady is priced comparably to other common third-party veterinary diagnostics.

Not at all. In some cases, younger dogs are hormonally mature earlier than guidelines suggest while others may benefit from waiting. It’s about making informed decisions, not enforcing arbitrary delays.

Absolutely. The programme is designed to support informed choice. Our goal is to make client conversations clearer, not more complicated.

For dogs that return ‘pre-mature’ levels of androgen bioactivity, a retest after about 2-3 months is recommended depending on breed.

While physical changes (such as testicular enlargement) are observable, they are subjective and open to interpretation. NeuterReady measures androgen receptor bioactivity levels, a more accurate and repeatable method for determining hormonal maturity status.

Ready to Bring NeuterReady Into Your Practice?

Start making more confident, evidence-based neutering decisions – powered by real hormonal maturity data. Whether you’re looking to align with updated guidelines, enhance client

conversations, or simply avoid the risks of early desexing, NeuterReady makes it easy to integrate science-led insights into everyday veterinary workflows.

Partner with NationWide Laboratories and bring NeuterReady into your clinic today.